![]() ![]() Among bacterial species identified, Gardnerella and Enterococcus had a relative abundance >2% in the ccRCC group. 52.6 years, p 2% in the ccRCC group.Ĭonclusions: Urine samples from pathologically confirmed ccRCC patients revealed a younger and predominantly male population with decreased microbial diversity when compared to patients with renal cysts. Those with renal cysts were older and more often female when compared to those with clear cell carcinoma (65.4 years vs. ![]() Urine samples underwent 16S rRNA sequencing. Results: Seventeen patients with renal cysts and 18 patients with confirmed ccRCC provided 53 total urine samples, including one sample at the time of initial clinic presentation and a second sample at a median of 159 days (range 84‐595) later for renal cyst patients and 102 days postoperatively (range 44‐401) for ccRCC patients. Bacterial diversity, as determined by the number of observed species (alpha diversity) and dissimilarity (beta diversity) between samples, was compared between the groups using PERMANOVA analysis. All urine samples were analyzed using 16S rRNA sequencing. Patients with renal cysts provided urine samples at two separate office visits. Patients with presumed renal cell carcinoma provided samples at their pre‐operative visit and post‐operative visit. Methods: Twenty patients with renal masses suspicious for renal cancer and 20 patients with a simple or very low‐risk cyst(s) provided urine samples at two office visits. The purpose of this study was to examine the differences in the urinary microbiome between patients with simple or low‐risk renal cyst(s) and individuals with newly diagnosed, clear cell renal cell carcinoma (ccRCC). ![]() Data regarding which bacterial flora are favorable and which may be detrimental remain sparse. Introduction & Objective: The urogenital tract has only recently been found to harbor its own microbiome. R Bhatt, A Brevik, KL Morgan, S Ali, A Peta, L Xie, R Karani, P Jiang, RM Patel, J Landman MPBS1‐01 The Influence of Renal Cancer on the Urinary Microbiome: A Pilot Study ![]()
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